Ontology Fingerprints

What is Ontology Fingerprint?
Ontology Fingerprint for a gene or a disease is a set of Gene Ontology terms overrepresented in the PubMed abstracts linked to a gene or disease along with those termsĄŻ corresponding enrichment p-values.

Yeast OntoFin Networks
Gene Name Entity Disambiguation



Qin T, Matmati N, Tsoi LC, Mohanty BK, Gao N, Tang J, Lawson AB, Hannun YA, Zheng WJ. Finding pathway-modulating genes from a novel Ontology Fingerprint-derived gene network. Nucleic Acids Res. 2014 Jul 24. pii: gku678. [Epub ahead of print] PubMed PMID: 25063300.


Qin T, Tsoi LC, Sims KJ, Lu X, Zheng WJ. Signaling network prediction by the Ontology Fingerprint enhanced Bayesian network. BMC Syst Biol. 2012;6 Suppl 3:S3. doi: 10.1186/1752-0509-6-S3-S3. Epub 2012 Dec 17. PubMed PMID: 23282239; PubMed Central PMCID: PMC3524013.


Tsoi LC, Boehnke M, Klein RL, Zheng WJ. Evaluation of genome-wide association study results through development of ontology fingerprints. Bioinformatics. 2009 May 15;25(10):1314-20. doi: 10.1093/bioinformatics/btp158. Epub 2009 Apr 5. PubMed PMID: 19349285; PubMed Central PMCID: PMC2732313.

W. Jim Zheng, Ph.D.
Associate Professor
Associate Director
Center for Computational Biomedicine
School of Biomedical Informatics
University of Texas Health Science Center at Houston
7000 Fannin St. Suite 600
Houston, TX 77030
Phone: (713) 500 3641
Email: wenjin.j.zheng@uth.tmc.edu